north america – Top Clusters http://topclusters.org/ Mon, 28 Feb 2022 19:02:09 +0000 en-US hourly 1 https://wordpress.org/?v=5.9.3 https://topclusters.org/wp-content/uploads/2021/10/icon-5-100x100.png north america – Top Clusters http://topclusters.org/ 32 32 Trend analysis of central sensitization https://topclusters.org/trend-analysis-of-central-sensitization/ Wed, 23 Feb 2022 17:08:53 +0000 https://topclusters.org/?p=882 Zhuo Li,1,2,* Chi Xu,2,* Jun Fu,2 Maimaiti Zulipikaer,2 Tao Deng,2 Jiying Chen2 1School of Medicine, Nankai University, Tianjin, People’s Republic of China; 2Department of Orthopedic Surgery, Chinese PLA General Hospital, Beijing, People’s Republic of China Correspondence: Jiying Chen, Department of Orthopedic Surgery, Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing, 100853, People’s […]]]>

Zhuo Li,1,2,* Chi Xu,2,* Jun Fu,2 Maimaiti Zulipikaer,2 Tao Deng,2 Jiying Chen2

1School of Medicine, Nankai University, Tianjin, People’s Republic of China; 2Department of Orthopedic Surgery, Chinese PLA General Hospital, Beijing, People’s Republic of China

Correspondence: Jiying Chen, Department of Orthopedic Surgery, Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing, 100853, People’s Republic of China, Tel +86 10 66938104, Fax +86 10 68216336, Email [email protected]

Background: Central sensitization refers to a state of hypersensitivity in the central nervous system and is associated with the development and maintenance of chronic pain. Central sensitization plays an essential role in various diseases. Nevertheless, there has been no bibliometric analysis before in this field. The purpose of this study was to provide critical themes and trends in the area of central sensitization, to build a network of knowledge, and to facilitate the future development of relevant basic and clinical research.
Methods: Publications on central sensitization were extracted from the Science Citation Index-Expanded. We used R software to systematically analyze the countries, institutions, authors, journals, references, and keywords of the publications. Besides, conceptual structure, intellectual structure, and social structure were constructed.
Results: A total of 4466 publications were included. Research in the field of central sensitization generally showed a steady upward trend. The three structural networks showed that the United States is the leading country in this field. Arendt-Nielsen L and Woolf CJ were the most productive and influential authors, respectively. “Pain” was the journal with the most studies. Most journals that published and cited articles about central sensitization were academically influential. Cluster analysis revealed that research in central sensitization contains three main conceptual clusters, and the themes of research evolve frequently. Current research focuses on the pathogenesis of central sensitization in neuropathic pain, the role of central sensitization in different diseases, and related clinical double-blind trials.
Conclusion: Central sensitization received widespread attention. The United States led the way in academic activity. In this field, the current situation of cooperation and communication between different countries and institutions is positive. The present research hotspots were the pathogenesis of central sensitization in neuropathic pain, the role of central sensitization in different diseases, and related clinical double-blind trials.

Keywords: central sensitization, bibliometric analysis, pain, co-word, co-citation, collaboration network

Introduction

Pain is one of the most common clinical symptoms, leading to a decrease in the quality of life and an increase in health care expenditures.1,2 In the United States alone, approximately 100 million adults suffer from chronic pain and it costs $600 billion each year.3 Nowadays, more and more researches focus on the central sensitization (CS) of pain. CS, formally proposed by Woolf et al in 1988, refers to a state of hypersensitivity in the nervous system and is associated with the development and maintenance of chronic pain.4 In the state of CS, pain-related signaling pathways are hypersensitive to noxious and non-noxious stimuli. Besides, CS plays a crucial role in the evolution from acute to chronic pain.5 To a certain extent, pain is a measure of self-protection. However, chronic pain in a pathological state can be extremely disturbing to physical and mental health. When CS occurs, the nervous system is “provoked”. It is in a constant state of hyperresponsiveness, which lowers the pain threshold and continues to maintain pain after the external stimulus has disappeared or diminished.

CS can be present in many conditions with chronic pain, including fibromyalgia,6 endometriosis,7 chronic low back pain,8,9 hidradenitis suppurativa,10 osteoarthritis,6,11 rheumatoid arthritis and chronic migraine.12 Besides, complex regional pain syndrome (CRPS), also known as Sudeck’s atrophy, is also highly associated with CS and is characterized by significant autonomic and inflammatory features.13,14 In addition, in procedures such as hip and knee arthroplasty, spinal fusion, ovariohysterectomy, and oral surgery, CS can aggravate postoperative pain and severely reduce the postoperative quality of life.15–21

In terms of pathogenesis, CS is a broad topic that encompasses distorted sensory processing in the central nerve system (CNS),22 malfunctioning of descending pain-inhibitory mechanisms,23 enhanced activity of pain-facilitatory mechanisms,24 and long-term potentiation of the neural synapses in the anterior cingulate cortex.25 The above-mentioned pathological conditions will gradually lead to CS. This process can start with peripheral sensitization and then progress to advanced CS characterized by allodynia and diffuse hyperalgesia.26 Synaptic plasticity, influenced by environmental and individual genetic factors, is a critical element in CS process. Moreover, neuroplasticity in chronic pain syndromes has been of great interest to clinicians and researchers in recent decades.

Bibliometrics is a cross-cutting discipline that uses mathematical and statistical methods to quantitatively analyze a variety of specific indicators such as authors, citations, and keywords of the literature. With its help, we can also construct a network of knowledge in a particular field. Unlike other methods, bibliometrics can provide more accurate and credible reports through a systematic, reproducible, and modular process of literature analysis. It can simultaneously manage and handle large amounts of literature information, uncover intrinsic connections in the data, reveal the current state and development process of the discipline, and present the current scientific landscape of the research field.27,28

Bibliometric analysis has been applied in cutting-edge medical fields, such as COVID-1929 and single-cell sequencing.30 To the best of our knowledge, this is the first bibliometric study in the field of CS. The purpose of this study was to provide critical themes and trends in the area of CS, to build a network of knowledge, to get an overview of academic collaborations, and to facilitate the future development of relevant basic and clinical research.

Materials and Methods

The data for this study were extracted from the Science Citation Index Expanded (SCI-EXPANDED) database of the Clarivate Analytics Web of Science Core Collection. The data search strategy included the topic “central sensitization”, and the time span was set to 1998–2020. A total of 4710 articles were retrieved. Two other authors independently reviewed the titles and abstracts of the literature. We excluded special types of publications such as book chapters, editorial materials, corrections, and proceedings papers, and obtained a total of 4466 articles for further analysis. We exported 4466 articles in the form of all records and references and saved them as BibTex files. All data were downloaded within one day on September 15, 2021 to avoid deviations caused by database updates.

We summarized and analyzed the main bibliometric indicators of the selected literature, including the number of articles, journals, keywords, citations, author distribution, and collaborations. We used Author Appearances (AA) to represent the total frequency of all authors in all publications. Besides, we calculated the collaboration index (CI), which is another metric used to quantify collaboration between authors and can be calculated as total authors of multi-authored articles/total multi-authored articles. Besides, we used total citations and local citations to assess the impact of the articles. The former counts citations received by a selected article “all over the world”, while the latter counts only citations received from documents included in our collection (4466 articles). Local citations measure the impact of a document in the analyzed collection. What’s more, we assessed the author’s scholarly achievements by H-index, G-index, and M-index. It is well known that H-index is an author’s number of published articles (h) each of which has been cited in other papers at least h times. The m-index is defined as H-index/n, where n is the number of years since the first published paper of the author. Additionally, given a set of articles ranked in decreasing order of the number of citations that they received, the G-index is the unique largest number such that the top g articles received together at least g2 citations. In further, we evaluated the academic impact of the journals based on Journal Citation Reports (JCR). Briefly, journals in a field are ranked according to their impact factors, with the top 25% (including 25%) being classified as Q1, the top 25% to 50% (including 50%) as Q2, the top 50% to 75% (including 75%) as Q3, and those after 75% as Q4. As for keywords, there were two types of keywords: those provided by the authors and those automatically extracted by the system (KeyWord Plus). KeyWords Plus provides additional search terms extracted from the titles of articles cited by authors in their bibliographies and footnotes in the ISI (now Clarivate Analytics) database. It substantially augments title-word and author-keyword indexing.31

Additionally, we constructed three structural networks to enable deeper mining of the literature structure. Nodes in the network represented high-frequency items (eg, articles, journals, or authors), and their sizes indicated the frequency of occurrence. The more frequently an item appears, the larger the size of the corresponding node. Similarly, the lines between nodes represented their connectivity or interactions. The thickness of the line reflected the degree or strength of co-citation or co-occurrence of the nodes.32,33 We applied three metrics to measure the centrality of nodes in the network. All shortest paths of any two nodes in the network were calculated, and if many of them passed through a node, then the Betweenness Centrality of this node was considered high. If the shortest distance from a node to other nodes was small, then we considered the Closeness Centrality of the node to be high. The PageRank score was obtained by link analysis, which was an unsupervised learning method based on Markov chains on graph data.34

The conceptual structure was constructed by co-word analysis based on the co-occurrence frequency of keywords in the whole set. More specifically, it was mapped using the co-occurrence of KeyWords Plus. We set the following parameters: the normalization method was the association, the number of nodes was 50, the repulsion force was 0.1, the minimum number of edges was 2, and we removed isolated nodes. In addition, we constructed the intellectual structure of the CS field by co-citation analysis. Co-citation can be seen as the counterpart of bibliographic coupling. As far as references are concerned, two articles are coupled if at least one common citation source appears in the references of both articles. Co-citation, on the other hand, reflects two cited papers being cited by one paper at the same time. The bibliographic coupling reflects a fixed and long-lasting relationship between the papers, while the co-citation reflects a changing or temporary relationship. We set the number of nodes to 50 and constructed a co-citation network of articles, authors, and journals. Besides, we showed the social structure of the CS by collaboration network analysis. The nodes in the network can represent articles, journals, institutions, or countries, and they were linked by co-authors.

Data processing and analysis were performed by R software (version 4.1.0). We completed the bibliometric analysis and plotted figures using the R package called bibliometrix. For cluster analysis, the Louvain method was chosen as the algorithm.35

Results

General Information and Publication Trends

As shown in Figure 1 and Table 1, 4466 publications on CS have been published in the past 23 years. During this 23-year period, there had been a substantial increase in the number of papers on CS. The overall analysis of the publications showed that they were written by 13,127 authors and the average citations per document were 40.1. These publications had 833 journals and a total of 119,823 references. Besides, the number of KeyWords Plus and author’s keywords were 8643 and 6850, respectively. Interestingly, the average article citations per year fluctuated around four with two peaks: in 2004 and 2019 with 8.2 and 5.8, respectively, indicating that newly published articles also had a high impact.

Figure 1 The number of publications with the theme of CS indexed by SCI-E from 1998 to 2020.

Abbreviations: CS, central sensitization; SCI-E, Science Citation Index-Expanded.

Publication Performances: Countries, Institutions, and Authors

The publication country was selected based on the corresponding author. As shown in Table 2, the most productive country in terms of CS was the United States of America (USA) (n = 1379, 30.9%), followed by China (n = 432, 9.7%) and Germany (n = 262, 5.9%). However, although the United States has the largest number of multiple countries publications (MCPs), it does not account for a high percentage of all publications. The most cited country was also USA (n = 87,030, average article citations (AAC, total citations divided by the number of articles) =63.11), followed by the United Kingdom (n = 11,313, AAC = 45.07) and Germany (n = 10,977, AAC = 41.9). The top three most productive institutions were University of Florida (n = 297), Aalborg University (n = 269) and Vrije Universiteit Brussel (n = 232) (Figure 2A). Six of the top ten most productive institutions were in the USA. The above data showed that the USA was the leader in CS research. In addition, Figure 2B showed the top ten most productive authors, and Figure 2C showed their annual articles published and cited information. Many authors had been deeply involved in the field of CS for more than ten years. From 1998 to 2020, Arendt-Nielsen L had published articles on CS almost every year. Nijs J and Meeus M, on the other hand, had been focusing on CS field research since 2007, while academic publications were more prolific after 2013. We analyzed authors’ academic indices (H-index, G-index, and M-index) based on this study’s article collection. Arendt-Nielsen L from Aalborg University not only had the highest number of publications but also had the highest academic indices (Supplementary Table 1).

Table 1 Main Information About Bibliometric Analysis

Table 2 Top 20 Productive Countries and Citations per Country

Figure 2 Top ten most productive institutions and authors. (A) Top ten most productive institutions; (B) Top ten most productive authors; (C) Top-Authors’ Production Over Time. The color of the dots represent the number of articles, and the size of the dots represent the TC per year.

Abbreviation: TC, total citations.

Highly Contributive Journals and Articles

The most productive source for article publication was “Pain” with 380 articles published during 1998–2020, followed by “Journal of Pain” (n = 118) and “European Journal of Pain” (n = 116) (Table 3). Most of the journals were in the field of pain research or neuroscience journals. Besides, the articles from “Pain” were the most cited, with 24,854 total citations. More importantly, the most cited journals in the references of 4466 included publications were also “Pain” with 29,410 citations. Most local cited articles referred to highly cited articles in the current data set, and can be considered as articles with significant academic influence in this field. The first ranked article was “Woolf et al, 2011”26 with 748 local citations and 2014 global citations, followed by “Latremoliere et al, 2009”36 with 664 local citations and 1731 global citations (Supplementary Table 2). Both review articles were published on “Pain”.

Table 3 Top 20 Journals Related to Central Sensitization

Conceptual Structure

Based on the co-occurrence analysis of 8643 KeyWords Plus, we revealed that they can be classified into three different clusters (Figure 3). We ranked them in each cluster based on their network centrality. In cluster 1, “central sensitization” (Betweenness Centrality:121.20) had the highest centrality, followed by “pain” and “hyperalgesia”. Cluster 2 contained only two elements, “sensitization” and “central”. However, cluster 3 revealed another topic closely linked to CS: “neuropathic pain” (Betweenness Centrality:21.58). “Spinal-cord”, “neurons”, and “activation” also belonged to the same cluster (Supplementary Table 3). We divided the 23-year time span of articles into three periods: 1998–2005; 2006–2012; and 2013–2020. As shown in Figure 4, in the first period of 1998–2005, we identified 12 thematic fields, of which “substance-p” and “central sensitization” were the most studied. In the second phase, the field of “neuropathic pain” emerged, which evolved from the previous nine thematic areas. “Temporal summation”, which evolved from three thematic areas, was also an important emerging concept during this period. Interestingly, in the recent period, many of the previous fields evolved into the final five key areas: “central sensitization”, “neuropathic pain”, “ double-blind”, “sensitization”, “low-back-pain”, and “brain”. These were the hot research topics and future directions in the field of CS.

Figure 3 Network visualization of KeyWords Plus (KWP) co-occurrence. The thickness of the connecting line between 2 keywords represents the strength of co-occurrence. The size of the KWP represents the index of their centrality.

Figure 4 Thematic evolution of KeyWords Plus in field of research on central sensitization 1998–2020. Three time slices: 1998–2005, 2006–2012, and 2013–2020.

Intellectual Structure

The most influential authors, articles, and journals were determined based on co-citation networks and cluster analysis. In articles and authors clustering, we obtained four main clusters, while in journals we obtained two (Figure 5). Figure 5A showed that “Woolf CJ”, “Arendt-Nielsen L”, “Burstein R” and “Treede RD” occupied the center of each of the four author clusters. The top five co-cited authors with the highest Betweenness Centrality were “Woolf CJ” (118.06) in cluster 1, and “Treede RD” (50.30), “Koltzenburg M” (34.07), “Melzack R” (31.42), and “Baron R” (26.11) in cluster 4 (Supplementary Table 4). “Price DD” (22.72) and “Burstein R” (13.78) were the most centralized in clusters 2 and 3, respectively. Figure 5B indicated that “Woolf CJ, 2011” and “Latremoliere A” were centered in the largest cluster of articles. In fact, six of the top 10 co-cited articles with the highest centrality were written by Woolf CJ, and these articles were in the center of cluster 1, cluster 2, and cluster 4. As for the co-cited journals, the “Journal of Neuroscience” and the “Pain” are the most centralized in clusters 1 and 2, respectively (Figure 5C). However, the “Pain” was the most centralized by a large margin. Most of the journals in cluster 1 were neuroscience journals, while the journals in cluster 2 seemed to be more focused on pain research. The above results indicated that “Woolf CJ” and the “Pain” were the most influential author and journal in the co-citation network, respectively.

Figure 5 Co-citation network analysis with the identification of only 2 co-citation clusters for (A) authors, (B) articles, and (C) journals.

Social Structure

Ten different clusters of authors were formed in the social structure of 4466 articles related to CS (Figure 6A). The authors with high centrality in the co-collaboration network were “Arendt-Nielsen L” in Cluster 1, “Nijs J” in Cluster 2, “Wang Y” in Cluster 3, and “Ji RR” in Cluster 4. Besides, the institutions reaching the highest centrality were “Aalborg University”, “Vrije Universiteit Brussel”, “Harvard University”, and “The University of Toronto” (Figure 6B). The most prominent countries with high centrality were the USA (619.21) in cluster 1, United Kingdom (54.87) in cluster 2, Spain (21.87) in cluster 3 (Figure 6C). China was in the same cluster as the US and also had a high degree of centrality (48.62). Simultaneously, we constructed an inter-country collaboration map based on the number of MCPs. In brief, it was created by mapping MCPs’ international partnerships to a global map to more visually show the state of global collaboration. The thicker the red line, the more frequent the collaboration. As shown in Figure 7, international cooperation in the field of CS was quite frequent. Specifically, the top five collaborations among countries, ranked by number of MCPs, were USA-China:100; USA-United Kingdom:68; USA-Germany:59; USA-Canada:53; USA-Denmark:47. The social structure suggested a good level of international collaboration in the field of CS, with the USA playing an influential role in the cooperation network.

Figure 6 Collaborations network among (A) authors, (B) institutions, and (C) countries.

Figure 7 Worldwide collaborations among countries in the field of central sensitization. The thicker the red line, the more frequent the collaboration.

Discussion

We applied a bibliometric analysis to elucidate the global scientific activity around the topic of CS to help scholars deepen their understanding of the scientific accumulation and potential future trends in CS research. We analyzed the most productive countries, institutions and authors, and the most contributive journals and articles in CS research. Besides, we constructed conceptual structure, knowledge structure, and social structure through network analysis and cluster analysis. To the best of our knowledge, this is the first bibliometric study in the field of CS.

It is well known that in recent years there had been a significant increase in the number of publications in the field of pain, such as pain after spinal cord injury,37 chronic postsurgical pain,38 etc. As shown in Figure 1, the number of CS-related articles was on a very steady upward trend, which indicated a great potential for future development. The USA was the most productive and most cited country. Besides, six of the top ten most productive institutions were in the USA. The above data showed that the USA is the leader in CS research. Similarly, bibliometric analyses in other specific pain areas had shown the USA was the leader in pain research, such as pain in the elderly,39 back pain,40 acupuncture for low back pain,41 and neuropathic pain.42 Many of the most productive authors had been deeply involved in this field for more than ten years, reflecting the progressive development of their research. In recent years, Arendt-Nielsen L, as the most productive author, had contributed to elucidating the role of CS in tension-type headache, chronic neck and shoulder pain, pelvic pain, and osteoarthritis pain.43–47 Regarding the number of publications and the citations, “Pain” was the most influential journal. Besides, 7 of the top 20 most productive journals belonged to JCR Q1, which showed the importance of CS field research.

Most local cited articles can provide us with more helpful information. Two reviews written by Woolf and Latremoliere described in detail the concept and mechanisms of CS. They elaborated on its relationship to central neuroplasticity and implications for the diagnosis and treatment of pain.26,36 Ji et al analyzed the molecular mechanisms underlying the generation and maintenance of CS and learning memory.48 Notably, they suggested that although synaptic plasticity changes differ between the two, they share striking similarities. Using patch-clamp recordings in lamina II neurons of isolated spinal cord slices, pro-inflammatory cytokines (interleukin-1β, interleukin-6, and tumor necrosis factor-α) had been shown to induce CS through distinct and overlapping synaptic mechanisms in superficial dorsal horn neurons.49 In addition, these cytokines may further induce long-term synaptic plasticity through cAMP response element-binding protein (CREB)-mediated downstream responses. The study by Arendt-Nielsen et al revealed the role of CS in painful knee osteoarthritis and received 518 global citations and 167 local citations.50

In the conceptual structure we constructed, the essential clusters were cluster 1: “Central Sensitization” and cluster 2: “Neuropathic Pain”. The concepts in both clusters have been very active over the past 20 years: cluster 1 – which includes the terms pain, mechanism, hyperalgesia, modulation, and temporal summation – is the most prominent and demonstrates the core concepts of the CS field. As well, another primary cluster “Neuropathic Pain” – which includes the terms spinal cord, neurons, activation, substance-p, long-term potentiation, and peripheral nerve injury – mainly explores the neuropathological alterations of CS.26,51–53 We analyzed the thematic evolution of different time slices, which can highlight the complexity of research in the CS field. Interestingly, in the recent period, many of the previous fields evolved into the final five key fields: “central sensitization”, “neuropathic pain”, “double-blind”, “sensitization”, “low-back-pain”, and “brain “. Several bibliometric analyses showed similar interesting results. “Double blind” was also one of the most commonly used keywords in neuropathic pain research.42 Besides, “central sensitization” was the research development trends and focus in the pain field after spinal cord injury.37 Nowadays, there are a growing number of double-blind studies advancing the clinical application of the concept of CS, deepening the understanding of a variety of diseases such as osteoarthritis and migraine.54–57 CS-related changes in functional brain activity can be observed in rats with endometriosis-related pain: enhanced ReHo signaling in the cingulate cortex, thalamus, and hippocampus, which may be due to neuronal apoptosis or hyperactivity.58 In addition, since the brain-derived neurotrophic factor (BDNF) is an essential driver of neuroplasticity, targeting BDNF may be a potential therapeutic target for improving CS (blockade of the adenosine A2A receptor, antagonizing NMDA receptors, or blocking the proteinase-activated receptors 2-NK-κβ signaling pathway).59 The importance of CS in chronic low back pain has been demonstrated. Similarly, in acute lower back pain CS may co-exist with other psychological factors (high sensitivity and negative psychological state) and contribute to the persistence of pain.60

Intellectual structure analysis revealed the current knowledge base of CS research, and it indicated that “Woolf CJ” and the “Pain” were the most influential author and journal in the co-citation network, respectively. Although “Woolf CJ” is not on the list of the most productive authors, his papers have a considerable impact on the CS field. The most contributive article is “Woolf et al, 2011”8 with 748 local citations and 2011 global citations, which can also confirm the significance of his publications. He revealed that IL1β-mediated induction of Cox-2 in the central nervous system promoted hypersensitivity of inflammatory pain.61 Besides, he confirmed that bradykinin activated multiple kinases in dorsal horn neurons resulting in hyperalgesia.62 On a more fundamental level, the papers located at the center of each cluster in Figure 5B can represent recognized carriers of knowledge in the CS field. At the same time, they can also contribute to the emergence of new research.

We constructed social structures at three levels: authors, research institutions, and countries. What is exciting is that there is a good co-collaboration network in the CS field, especially between countries, which is not available in some other studies.32 But we should also note the imbalance between the different geographic regions: North America, Europe, East Asia, and Oceania are the regions where collaboration is much more frequent. The lack of deeper international cooperation may be a real obstacle to more remarkable progress in CS research in the future. With the help of academic journals and professional associations, it is proposed that scholars from different research areas and professional backgrounds should work collaboratively to optimize this situation further.63

The present study also has some limitations that need to be solved. First, we only included articles from the Web of Science Core Collection; therefore, this study cannot be an exhaustive review of the entire literature in the CS field. Second, the search results of this study are not representative of the real-time situation due to the continuous updating of the relevant literature. Third, although the publications included in this study were manually screened, the quality of the collected literature was uneven, which may reduce the credibility of the results. It is undoubtedly important to select as much relevant publications as possible in order to obtain an overall picture of research in a given field. Therefore, stringent inclusion criteria for the publications may be a double-edged sword. In future studies we may be able to assess or avoid the uneven quality of the literature by setting different inclusion criteria, classification according to different definitions of CS, or based on impact factor or number of citations, etc. Fourth, CS can only be assessed in animals and in humans we can only assess a proxy, which may introduce uncertainty into the results. In future research, we may be able to precisely define CS in humans or animals separately and analyze it separately. Finally, we cannot assess the incidence of self-citation when constructing the knowledge structure.

Our study was based on the R package “bibliometrix”, and three structural networks were constructed. Overall, we established a model that can be used to keep track on the area in the future with the option to see changes in the landscape. Through periodic analysis, we can obtain historical trajectories and real-time dynamics of CS research. We hope this is an innovative exploration in this field.

Conclusion

Studying the mechanism of CS and its role in disease diagnosis and treatment has excellent research value and broad clinical application prospects. Using the R package named bibliometrix for bibliometric analysis and visualization, research in CS generally showed a steady upward trend. The three structural networks showed that the USA is the leading country in this research. Arendt-Nielsen L and Woolf CJ were the most productive and influential authors, respectively. The current situation of cooperation and communication between different countries and institutions is positive. Most journals that publish and cite articles about CS were academically influential, indicating that CS had received widespread attention. Cluster analysis revealed that research in the field of CS contained three main conceptual clusters, and the themes of research evolved frequently. The current research focused on the pathogenesis of CS in neuropathic pain, the role of CS in different diseases, and related clinical double-blind trials.

Abbreviations

CS, central sensitization; CNS, central nerve system; SCI-EXPANDED, Science Citation Index Expanded; BDNF, brain-derived neurotrophic factor; KWP, KeyWords plus; MCP, multiple countries publications.

Data Sharing Statement

The raw data can be directly obtained from the Web of Science Core Collection (WoSCC) database.

Ethics Approval and Informed Consent

This study did not include any patient information. Thus, the requirement for ethics approval was waived.

Acknowledgments

This work was supported by National Key Research and Development Program of China (No. 2020YFC2004900).

Disclosure

Zhuo Li and Chi Xu are the co-first authors. The authors report no conflicts of interest in this work.

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17. Kaka U, Rahman NA, Abubakar AA, et al. Pre-emptive multimodal analgesia with tramadol and ketamine-lidocaine infusion for suppression of central sensitization in a dog model of ovariohysterectomy. J Pain Res. 2018;11:743–752. doi:10.2147/JPR.S152475

18. Kim MS, Koh IJ, Choi KY, Seo JY, In Y. Minimal clinically important differences for patient-reported outcomes after TKA depend on central sensitization. J Bone Joint Surg Am. 2021;103(15):1374–1382. doi:10.2106/JBJS.20.02138

19. Kim MS, Koh IJ, Sohn S, Kang BM, Kwak DH, In Y. Central sensitization is a risk factor for persistent postoperative pain and dissatisfaction in patients undergoing revision total knee arthroplasty. J Arthroplasty. 2019;34(8):1740–1748. doi:10.1016/j.arth.2019.03.042

20. Koh IJ, Kang BM, Kim MS, Choi KY, Sohn S, In Y. How does preoperative central sensitization affect quality of life following total knee arthroplasty? J Arthroplasty. 2020;35(8):2044–2049. doi:10.1016/j.arth.2020.04.004

21. Wylde V, Sayers A, Odutola A, Gooberman-Hill R, Dieppe P, Blom AW. Central sensitization as a determinant of patients’ benefit from total hip and knee replacement. Eur J Pain. 2017;21(2):357–365. doi:10.1002/ejp.929

22. Staud R, Craggs JG, Robinson ME, Perlstein WM, Price DD. Brain activity related to temporal summation of C-fiber evoked pain. Pain. 2007;129(1–2):130–142. doi:10.1016/j.pain.2006.10.010

23. Meeus M, Nijs J, Van de Wauwer N, Toeback L, Truijen S. Diffuse noxious inhibitory control is delayed in chronic fatigue syndrome: an experimental study. Pain. 2008;139(2):439–448. doi:10.1016/j.pain.2008.05.018

24. Meeus M, Nijs J. Central sensitization: a biopsychosocial explanation for chronic widespread pain in patients with fibromyalgia and chronic fatigue syndrome. Clin Rheumatol. 2007;26(4):465–473. doi:10.1007/s10067-006-0433-9

25. Zhuo M. A synaptic model for pain: long-term potentiation in the anterior cingulate cortex. Mol Cells. 2007;23(3):259–271.

26. Woolf CJ. Central sensitization: implications for the diagnosis and treatment of pain. Pain. 2011;152(3 Suppl):S2–S15. doi:10.1016/j.pain.2010.09.030

27. Durieux V, Gevenois PA. Bibliometric indicators: quality measurements of scientific publication. Radiology. 2010;255(2):342–351. doi:10.1148/radiol.09090626

28. Ellegaard O, Wallin JA. The bibliometric analysis of scholarly production: how great is the impact? Scientometrics. 2015;105(3):1809–1831. doi:10.1007/s11192-015-1645-z

29. Xia D, Yao R, Wang S, Chen G, Wang Y. Mapping trends and hotspots regarding clinical research on COVID-19: a bibliometric analysis of global research. Front Public Health. 2021;9:713487. doi:10.3389/fpubh.2021.713487

30. Wang Q, Yang KL, Zhang Z, et al. Characterization of global research trends and prospects on single-cell sequencing technology: bibliometric analysis. J Med Internet Res. 2021;23(8):e25789. doi:10.2196/25789

31. Chong Y, Long X, Ho YS. Scientific landscape and trend analysis of keloid research: a 30-year bibliometric review. Ann Transl Med. 2021;9(11):945. doi:10.21037/atm-21-508

32. Fortuna G, Aria M, Piscitelli A, Mignogna MD, Klasser GD. Global research trends in complex oral sensitivity disorder: a systematic bibliometric analysis of the structures of knowledge. J Oral Pathol Med. 2020;49(6):565–579. doi:10.1111/jop.13077

33. Gonzalez-Alcaide G, Calafat A, Becona E, Thijs B, Glanzel W. Co-citation analysis of articles published in substance abuse journals: intellectual Structure and Research Fields (2001–2012). J Stud Alcohol Drugs. 2016;77(5):710–722. doi:10.15288/jsad.2016.77.710

34. Brin S, Page L. The anatomy of a large-scale hypertextual Web search engine. Comput Netw ISDN Syst. 1998;30(1):107–117. doi:10.1016/S0169-7552(98)00110-X

35. Subelj L, Bajec M. Unfolding communities in large complex networks: combining defensive and offensive label propagation for core extraction. Phys Rev E Stat Nonlin Soft Matter Phys. 2011;83(3 Pt 2):036103. doi:10.1103/PhysRevE.83.036103

36. Latremoliere A, Woolf CJ. Central sensitization: a generator of pain hypersensitivity by central neural plasticity. J Pain. 2009;10(9):895–926. doi:10.1016/j.jpain.2009.06.012

37. Wang YZ, Wu CC, Wang XQ. Bibliometric Study of Pain after Spinal Cord Injury. Neural Plast. 2021;2021:6634644. doi:10.1155/2021/6634644

38. Li Q, Dai W, Chen X, Su D, Yu W, Gu X. Publication trends and hot spots in chronic postsurgical pain (CPSP) research: a 10-year bibliometric analysis. J Pain Res. 2021;14:2239–2247. doi:10.2147/JPR.S300744

39. Zhao Y, Zhang Z, Guo S, et al. Bibliometric analysis of research articles on pain in the elderly published from 2000 to 2019. J Pain Res. 2021;14:1007–1025. doi:10.2147/JPR.S283732

40. Huang W, Wang L, Wang B, Yu L, Yu X. Top 100 cited articles on back pain research: a citation analysis. Spine. 2016;41(21):1683–1692. doi:10.1097/BRS.0000000000001736

41. Liang YD, Li Y, Zhao J, Wang XY, Zhu HZ, Chen XH. Study of acupuncture for low back pain in recent 20 years: a bibliometric analysis via CiteSpace. J Pain Res. 2017;10:951–964. doi:10.2147/JPR.S132808

42. Xiong HY, Liu H, Wang XQ. Top 100 most-cited papers in neuropathic pain from 2000 to 2020: a Bibliometric Study. Front Neurol. 2021;12:765193. doi:10.3389/fneur.2021.765193

43. Arendt-Nielsen L, Morlion B, Perrot S, et al. Assessment and manifestation of central sensitisation across different chronic pain conditions. Eur J Pain. 2018;22(2):216–241. doi:10.1002/ejp.1140

44. Grundstrom H, Gerdle B, Alehagen S, Bertero C, Arendt-Nielsen L, Kjolhede P. Reduced pain thresholds and signs of sensitization in women with persistent pelvic pain and suspected endometriosis. Acta Obstet Gynecol Scand. 2019;98(3):327–336. doi:10.1111/aogs.13508

45. Iwabuchi SJ, Xing Y, Cottam WJ, et al. Brain perfusion patterns are altered in chronic knee pain: a spatial covariance analysis of arterial spin labelling MRI. Pain. 2020;161(6):1255–1263. doi:10.1097/j.pain.0000000000001829

46. Monteiro BP, Otis C, Del Castillo JRE, et al. Quantitative sensory testing in feline osteoarthritic pain – A systematic review and meta-analysis. Osteoarthritis Cartilage. 2020;28(7):885–896. doi:10.1016/j.joca.2020.04.006

47. Petersen KK, Olesen AE, Simonsen O, Arendt-Nielsen L. Mechanistic pain profiling as a tool to predict the efficacy of 3-week nonsteroidal anti-inflammatory drugs plus paracetamol in patients with painful knee osteoarthritis. Pain. 2019;160(2):486–492. doi:10.1097/j.pain.0000000000001427

48. Ji RR, Kohno T, Moore KA, Woolf CJ. Central sensitization and LTP: do pain and memory share similar mechanisms? Trends Neurosci. 2003;26(12):696–705. doi:10.1016/j.tins.2003.09.017

49. Kawasaki Y, Zhang L, Cheng JK, Ji RR. Cytokine mechanisms of central sensitization: distinct and overlapping role of interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha in regulating synaptic and neuronal activity in the superficial spinal cord. J Neurosci. 2008;28(20):5189–5194. doi:10.1523/JNEUROSCI.3338-07.2008

50. Arendt-Nielsen L, Nie H, Laursen MB, et al. Sensitization in patients with painful knee osteoarthritis. Pain. 2010;149(3):573–581. doi:10.1016/j.pain.2010.04.003

51. Meacham K, Shepherd A, Mohapatra DP, Haroutounian S. Neuropathic pain: central vs. peripheral mechanisms. Curr Pain Headache Rep. 2017;21(6):28. doi:10.1007/s11916-017-0629-5

52. Silva RL, Lopes AH, Guimaraes RM, Cunha TM. central sensitization. Neurobiol Dis. 2017;105:109–116. doi:10.1016/j.nbd.2017.06.001

53. Wang F, Ma SB, Tian ZC, et al. Nociceptor-localized cGMP-dependent protein kinase I is a critical generator for central sensitization and neuropathic pain. Pain. 2021;162(1):135–151. doi:10.1097/j.pain.0000000000002013

54. Hughes SW, Ward G, Strutton PH. Anodal transcranial direct current stimulation over the primary motor cortex attenuates capsaicin-induced dynamic mechanical allodynia and mechanical pain sensitivity in humans. Eur J Pain. 2020;24(6):1130–1137. doi:10.1002/ejp.1557

55. Kim MS, Koh IJ, Sung YG, Park DC, Na JW, In Y. Preemptive duloxetine relieves postoperative pain and lowers wound temperature in centrally sensitized patients undergoing total knee arthroplasty: a randomized, double-blind, placebo-controlled trial. J Clin Med. 2021;10:13.

56. Mohamadi M, Rojhani-Shirazi Z, Assadsangabi R, Rahimi-Jaberi A. Can the positional release technique affect central sensitization in patients with chronic tension-type headache? A Randomized Clinical Trial. Arch Phys Med Rehabil. 2020;101(10):1696–1703. doi:10.1016/j.apmr.2020.05.028

57. Tavares DRB, Okazaki JEF, Santana MVA, et al. Motor cortex transcranial direct current stimulation effects on knee osteoarthritis pain in elderly subjects with dysfunctional descending pain inhibitory system: a randomized controlled trial. Brain Stimul. 2021;14(3):477–487. doi:10.1016/j.brs.2021.02.018

58. Zheng P, Jia S, Guo D, et al. Central sensitization-related changes in brain function activity in a rat endometriosis-associated pain model. J Pain Res. 2020;13:95–107. doi:10.2147/JPR.S232313

59. Nijs J, Meeus M, Versijpt J, et al. Brain-derived neurotrophic factor as a driving force behind neuroplasticity in neuropathic and central sensitization pain: a new therapeutic target? Expert Opin Ther Targets. 2015;19(4):565–576. doi:10.1517/14728222.2014.994506

60. Klyne DM, Moseley GL, Sterling M, Barbe MF, Hodges PW. Are signs of central sensitization in acute low back pain a precursor to poor outcome? J Pain. 2019;20(8):994–1009. doi:10.1016/j.jpain.2019.03.001

61. Samad TA, Moore KA, Sapirstein A, et al. Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature. 2001;410(6827):471–475. doi:10.1038/35068566

62. Kohno T, Wang H, Amaya F, et al. Bradykinin enhances AMPA and NMDA receptor activity in spinal cord dorsal horn neurons by activating multiple kinases to produce pain hypersensitivity. J Neurosci. 2008;28(17):4533–4540. doi:10.1523/JNEUROSCI.5349-07.2008

63. Jiang LC, Wang ZZ, Peng TQ, Zhu JJ. The divided communities of shared concerns: mapping the intellectual structure of e-Health research in social science journals. Int J Med Inform. 2015;84(1):24–35. doi:10.1016/j.ijmedinf.2014.09.003

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Cluster Munitions Market Size, Scope, Growth, Competitive Analysis – Textron Systems, IMI Systems, L-3 Fuzing And Ordnance Systems (L3 FOS), Lockheed Martin https://topclusters.org/cluster-munitions-market-size-scope-growth-competitive-analysis-textron-systems-imi-systems-l-3-fuzing-and-ordnance-systems-l3-fos-lockheed-martin/ Tue, 22 Feb 2022 02:54:27 +0000 https://topclusters.org/cluster-munitions-market-size-scope-growth-competitive-analysis-textron-systems-imi-systems-l-3-fuzing-and-ordnance-systems-l3-fos-lockheed-martin/ New Jersey, United States,- The latest report published by Verified Market Reports indicates that the Cluster munitions market is expected to accelerate sharply in the coming years. Analysts have studied market drivers, restraints, risks, and opportunities in the global market. The Cluster Munitions Market report shows the probable direction of the market in the coming […]]]>

New Jersey, United States,- The latest report published by Verified Market Reports indicates that the Cluster munitions market is expected to accelerate sharply in the coming years. Analysts have studied market drivers, restraints, risks, and opportunities in the global market. The Cluster Munitions Market report shows the probable direction of the market in the coming years along with its estimations. An accurate study aims to understand the market price. By analyzing the competitive landscape, the authors of the report have made excellent efforts to help readers understand the key business tactics that major companies are using to maintain market sustainability.

The report includes company profiles of almost all the major players in the Cluster Munitions Market. The Company Profiles section provides valuable analysis of strengths and weaknesses, business trends, recent advances, mergers and acquisitions, expansion plans, global presence, market presence and portfolios of products from major market players. This information can be used by players and other market participants to maximize their profitability and streamline their business strategies. Our competitive analysis also provides vital information that will help new entrants identify barriers to entry and assess the level of competitiveness in the cluster munitions market.

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Key Players Mentioned in the Cluster Munitions Market Research Report:

Textron Systems, IMI Systems, L-3 Fuzing And Ordnance Systems (L3 FOS), Lockheed Martin, NORINCO, Orbital ATK, Aeroteh, China Aerospace Science And Technology

Cluster Munitions Market Segmentation:

By Product Type, the market is primarily split into:

• Anti-tank cluster munitions
• Anti-personnel cluster munitions

By application, this report covers the following segments:

• Maneuver
• Defend

The global cluster munitions market is segmented on the basis of product, type. All of these segments were studied individually. The detailed investigation helps to evaluate the factors influencing the Cluster Munitions market. Experts analyzed the nature of development, investments in research and development, changing consumption patterns and the growing number of applications. In addition, analysts have also assessed the development of the economy around the cluster munitions market which will likely affect its development.

The regional analysis section of the report allows players to focus on high growth regions and countries that could help them expand their presence in the Cluster Munitions market. In addition to expanding their footprint in the Cluster Munitions market, regional analysis helps players increase sales while gaining a better understanding of customer behavior in specific regions and countries. The report provides CAGR, revenue, production, consumption and other important statistics and figures related to global and regional markets. It shows how different types, applications, and regional segments are advancing in the Cluster Munitions market in terms of growth.

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Scope of the Cluster Munitions Market Report

ATTRIBUTES DETAILS
ESTIMATED YEAR 2022
YEAR OF REFERENCE 2021
FORECAST YEAR 2029
HISTORICAL YEAR 2020
UNITY Value (million USD/billion)
SECTORS COVERED Types, applications, end users, and more.
REPORT COVER Revenue Forecast, Business Ranking, Competitive Landscape, Growth Factors and Trends
BY REGION North America, Europe, Asia-Pacific, Latin America, Middle East and Africa
CUSTOMIZATION SCOPE Free report customization (equivalent to up to 4 analyst business days) with purchase. Added or changed country, region and segment scope.

Geographic segment covered in the report:

The Cluster Munitions report provides information on the market area, which is sub-categorized into sub-regions and countries/regions. In addition to the market share in each country and sub-region, this chapter of this report also contains information on profit opportunities. This chapter of the report mentions the market share and growth rate of each region, country and sub-region over the estimated period.

• North America (USA and Canada)
• Europe (UK, Germany, France and rest of Europe)
• Asia-Pacific (China, Japan, India and the rest of the Asia-Pacific region)
• Latin America (Brazil, Mexico and rest of Latin America)
• Middle East and Africa (GCC and Rest of Middle East and Africa)

Answers to key questions in the report:

1. Who are the top five players in the cluster munitions market?

2. How will the cluster munitions market evolve in the next five years?

3. Which product and which application will occupy the lion’s share of the cluster munitions market?

4. What are the drivers and restraints of the cluster munitions market?

5. Which regional market will show the strongest growth?

6. What will be the CAGR and size of the cluster munitions market throughout the forecast period?

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Virtual Power Plant Market Share 2021 Industry Analysis, Business Challenges, Global Manufacturer Overview and Forecast 2030 – Instant Interview https://topclusters.org/virtual-power-plant-market-share-2021-industry-analysis-business-challenges-global-manufacturer-overview-and-forecast-2030-instant-interview/ Sat, 12 Feb 2022 09:16:23 +0000 https://topclusters.org/virtual-power-plant-market-share-2021-industry-analysis-business-challenges-global-manufacturer-overview-and-forecast-2030-instant-interview/ Market scenario Global Virtual Power Plant Market is expected to reach US$800 million by 2026 at a CAGR of 30.50% during the forecast period. Virtual Power Plant (VPP) refers to a group of small-scale generators, such as Power Units (CHPs) and Combined Heat and Standby Generators, Biogas Plants, which collectively act as one large Power […]]]> ]]> Eyelash Extensions Market Size 2022 Industry Overview by Global Share, Top Key Players, COVID-19 Impact, Regional Analysis and Forecast to 2030 – The Tech Talk https://topclusters.org/eyelash-extensions-market-size-2022-industry-overview-by-global-share-top-key-players-covid-19-impact-regional-analysis-and-forecast-to-2030-the-tech-talk/ Mon, 07 Feb 2022 04:36:18 +0000 https://topclusters.org/eyelash-extensions-market-size-2022-industry-overview-by-global-share-top-key-players-covid-19-impact-regional-analysis-and-forecast-to-2030-the-tech-talk/ Global Eyelash Extensions Market development strategy before and after COVID-19, by analysis of company strategy, landscape, type, application, and Top 20 Countries, covers and analyzes the potential of the global Eyelash Extensions industry. eyelashes, providing statistical information on market dynamics, growth factors, major challenges, PEST analysis and market entry strategy Analysis, opportunities and forecast. The […]]]>

Global Eyelash Extensions Market development strategy before and after COVID-19, by analysis of company strategy, landscape, type, application, and Top 20 Countries, covers and analyzes the potential of the global Eyelash Extensions industry. eyelashes, providing statistical information on market dynamics, growth factors, major challenges, PEST analysis and market entry strategy Analysis, opportunities and forecast. The biggest strength of the report is to provide companies in the sector with a strategic analysis of the impact of COVID-19. At the same time, this report has analyzed the market of top 20 countries and introduced the market potential of these countries.

The Eyelash Extensions research report will also study the market share of major stakeholders in their global capacity as processors globally. This qualitative and quantitative analysis will include key product offerings, key differentiators, revenue share, market size, market status, and strategies. The report will also cover major global agreements, collaborations and partnerships that will soon change the market dynamics globally.

Click Link to Get Free Sample Copy of Report @ https://crediblemarkets.com/sample-request/eyelash-extensions-market-382004?utm_source=Amruta&utm_medium=SatPR

By top key players:

Revlon
NARS
Esqido Eyelashes
makeup geek
To kiss
Ultimate beauty
Shu uemura
Elf
Advantage
Ardel
Mac

By type:

Strip Eyelashes
Individual eyelashes
Cluster eyelashes
Others

By app:

Supermarket
Health and beauty retailer
E-commerce
Others

Eyelash Extensions Market: Regional Analysis Includes

  • Asia-Pacific (Vietnam, China, Malaysia, Japan, Philippines, Korea, Thailand, India, Indonesia and Australia)
  • Europe (Turkey, Germany, Russia UK, Italy, France, etc.)
  • North America (United States, Mexico and Canada.)
  • South America (Brazil etc.)
  • The Middle East and Africa (GCC countries and Egypt.)

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A few TOC points:

Chapter 1 is the basis of the whole report. In this chapter, we define the market concept and scope of the Eyelash Extensions market including product classification, application areas and whole area covered in the report.

Chapter 2 is the central idea of ​​the whole report. In this chapter, we provide a detailed introduction to our research methods and data sources.

chapter 3 focuses on analyzing the current competitive situation in the Eyelash Extensions market and providing background information, market data, product launches etc. of the main companies in the sector. At the same time, Chapter 3 includes the highlighted analysis – Strategies for the business to deal with the impact of COVID-19.

Chapter 4 provides breakdown data of different types of products, as well as market forecasts.

Different application areas have different product usage and development prospects.

Chapter 5 provides subdivision data of different application fields and market forecasts.

Chapter 6 includes detailed data of major regions of the world, including detailed data of major regions of the world. North America, Asia-Pacific, Europe, South America, Middle East and Africa.

Chapters 7-26 focus on the regional market. We have selected the most representative 20 countries among 197 countries in the world and made a detailed analysis and overview of the market development of these countries.

Chapter 27 focuses on the qualitative analysis of the market, providing analysis of market drivers, market development restraints, PEST analysis, industry trends under COVID-19, strategy analysis market entry, etc.

Do you have a specific question or requirement? Ask Our Industry Expert @ https://crediblemarkets.com/enquire-request/eyelash-extensions-market-382004?utm_source=Amruta&utm_medium=SatPR

Key points:

  • Define, describe and forecast the Eyelash Extensions product market by type, application, end-user, and region.
  • Provide an analysis of the company’s external environment and a PEST analysis.
  • Provide strategies to the business to deal with the impact of COVID-19.
  • To provide dynamic market analysis including market drivers, market development restraints.
  • Provide market entry strategy analysis for new players or players who are ready to enter the market, including market segment definition, customer analysis, distribution model, messaging and product positioning and pricing strategy analysis.
  • Track international market trends and provide analysis of the impact of the COVID-19 outbreak on major regions around the world.
  • Analyze stakeholder market opportunities and provide market leaders with competitive landscape details.

About Us

Credible Markets is a new era market research company with a firm grip on the pulse of global markets. Credible Markets has become a trusted source for business market research needs in a short period of time. We’ve partnered with leading market intelligence publishers and our report pool coverage spans all key industry verticals and thousands of micro-markets. The massive repository allows our clients to choose from recently released reports from a range of publishers who also provide in-depth analysis by region and country. Moreover, pre-booked research reports are among our best offers.

The collection of market intelligence reports is regularly updated to provide visitors with quick access to the latest market information. We provide round-the-clock support to help you reuse search parameters and benefit from a full range of reserved reports. After all, it’s about helping you make an informed, strategic decision on purchasing the right report that meets all your market research demands.

Contact us

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Global Automotive Instrument Cluster Market Development and Trend Report 2021-2026 https://topclusters.org/global-automotive-instrument-cluster-market-development-and-trend-report-2021-2026/ Wed, 02 Feb 2022 22:45:13 +0000 https://topclusters.org/global-automotive-instrument-cluster-market-development-and-trend-report-2021-2026/ Global “ Vehicle Instrument Cluster MarketThe 2020 report gives a comprehensive detail of key drivers, leading market players, key segments and regions. In addition, the experts have extremely studied various geological areas and presented a competitive scenario to help new entrants, major market players and investors determine the emerging economies. This information provided in the […]]]>

Global “ Vehicle Instrument Cluster MarketThe 2020 report gives a comprehensive detail of key drivers, leading market players, key segments and regions. In addition, the experts have extremely studied various geological areas and presented a competitive scenario to help new entrants, major market players and investors determine the emerging economies. This information provided in the Vehicle Instrument Cluster report would benefit market players to plan strategies for the prospects and gain a well-established position in the growth of the global Vehicle Instrument Cluster Market.

The study of the Vehicle Instrument Cluster market highlights important aspects such as drivers, challenges, restraints and expansion prospects prevailing in this particular industrial field.

Request a sample copy of this report @ https://www.getnewsalert.com/request-sample/12685

According to the report, the Vehicle Instrument Cluster Market is expected to grow significantly with a CAGR of XX% over 2020-2025, which is poised to accumulate considerable returns by the end of the forecast period. to analyse.

The nationwide lockdown, travel bans and movement restrictions, in all parts of the world, to curb the spread of COVID-19, are believed to have doomed many industries. Therefore, all companies are revising their finances and business strategies to incorporate the setup in the coming period. Through our in-depth analysis of this market, we offer recommendations for developing solid contingency plans to undo business uncertainties.

The report further entails a thorough examination of the various segmentations, allowing the reader to understand the overall impact on the market dynamics.

The main highlights of the Vehicle Instrument Cluster market report:

  • Impact of COVID-19 on Industry Growth Matrix
  • Figures related to sales volume, market compensation and market share
  • Endowed with the dynamics of the market
  • Growth outlook and expansion chart
  • PROCON study of direct and indirect sales channels
  • Profiles of Prominent Industry Traders, Dealers and Distributors

List of Segments in the Vehicle Instrument Cluster Market Report:

Geographic landscape: North America, Europe, Asia-Pacific, South America and Middle East and Africa

  • Industry forecast based on region and national level
  • Data on recorded sales volume, industry share held and accumulated profit margins
  • Overall earnings and estimated growth rate for each regional market

Product land: Hybrid cluster, analog cluster and digital cluster

  • Pricing model followed for each product
  • Accumulated revenue and market share counted for each type of product

Scope : Passenger vehicle, Utility vehicle, Two-wheeler, Agriculture and Off-road

  • Unit price and total product sales by application range
  • Extended revenue contribution by each application to the overall market valuation over the analysis period

Competitive hierarchy: Continental, Nippon Seiki, Visteon, Denso, Marelli, Yazaki, Bosch, Aptiv, Parker Hannifin, INESA, Stoneridge, Pricol, TYW, Desay SV and Dongfeng Electronic

  • Company profile, manufacturing unit information and products offered by each industry competitor
  • Services offered and data relating to product prices, sales, gross profit, revenue and market share for each company
  • SWOT analysis of each organization
  • Information relating to marketing matrix, marketing strategies, market concentration ratio and other important business facets

Answers to key questions in the report:

  • What will the market growth rate of Vehicle Instrument Cluster market?
  • What are the key factors driving the Global Vehicle Instrument Cluster Market?
  • Who are the leading companies in the Vehicle Instrument Cluster Market?
  • What are the market opportunities, market risk and market overview of the Vehicle Instrument Cluster market?
  • What are sales volume, revenue, and price analysis of top manufacturers of Vehicle Instrument Cluster market?
  • Who are the distributors, traders and dealers of Vehicle Instrument Cluster market?
  • What are the Vehicle Instrumentation Cluster market opportunities and threats faced by the vendors in the global Vehicle Instrumentation Cluster industries?
  • – What are sales, revenue, and price analysis by types and applications of Vehicle Instrument Cluster market?
  • What are sales, revenue, and price analysis by regions of Vehicle Instrument Cluster industries?

Customization request on this report @ https://www.getnewsalert.com/request-for-customization/12685

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Valuation Board Market Overview, Regional and National Forecast, In-Depth Analysis of Key Industry Vendor 2022-2028 https://topclusters.org/valuation-board-market-overview-regional-and-national-forecast-in-depth-analysis-of-key-industry-vendor-2022-2028/ Mon, 31 Jan 2022 08:42:06 +0000 https://topclusters.org/valuation-board-market-overview-regional-and-national-forecast-in-depth-analysis-of-key-industry-vendor-2022-2028/ the Valuation Consulting Market The report is a perfect foundation for people looking for in-depth study and analysis of the Assessment Board Market. This report contains various studies and information to help you understand your niche and focus on the major marketing channels in the regional and global Evaluation Board Market. Understand the competition and […]]]>

the Valuation Consulting Market The report is a perfect foundation for people looking for in-depth study and analysis of the Assessment Board Market. This report contains various studies and information to help you understand your niche and focus on the major marketing channels in the regional and global Evaluation Board Market. Understand the competition and take action based on their most important strengths, market size, demand in current and future years, supply chain information, business issues, analysis of the competition and pricing and supplier information will be presented to you. The report also contains information about major market players, Valuation Board applications, their type, trends and overall market share.

To launch your business plan based on our in-depth report, you will also receive a complete and accurate forecast and prediction along with projected numbers for the future. This will provide an overview of the market and help design solutions to leverage key profitable elements and gain clear market clarity for strategic planning. The information contained in the report is selected from various publications in our archives as well as many reputable paid databases. Moreover, the data is gathered with the help of distributors, raw material suppliers, and customers to ensure that the end result covers every detail of the Valuation Boards market making it a perfect tool for buyers serious about this study.

Get a FREE sample copy of this report with charts and graphs at: https://reportsglobe.com/download-sample/?rid=176987

Top Company Profiles:

  • NXP Semiconductors
  • Renesas electronics
  • Analog devices
  • STMicroelectronics
  • Maxim integrated
  • Texas Instruments
  • Broadcom
  • Renesas Electronics Corporation
  • Infineon Technologies
  • ON Semiconductor
  • Freescale
  • Fujitsu
  • Fairchild Semiconductor
  • Semiconductor cypress
  • Microchip

    Evaluation Board Market Segmentation:

    The Evaluation Board market is split by Type and by Application for the period 2022-2028, the growth between segments provides tips and correct forecasts for the sales by Type and Application in terms of volume and value. This analysis can help you grow your business by targeting qualified niche markets.

    By type:

  • IGBT evaluation board
  • MOSFET Evaluation Board
  • Other

    Per application:

  • Consumer electronics
  • Industrial
  • Other

    The Assessment Commission’s regional market analysis can be represented as follows:

    The whole regional segmentation has been studied based on recent and future trends and the market is forecast through the forecast period. The countries covered by the regional analysis of the Global Valuation Board Market Report are

    • Middle East and Africa (GCC countries and Egypt)
    • North America (United States, Mexico and Canada)
    • South America (Brazil…)
    • Europe (Turkey, Germany, Russia, Britain, Italy, France, etc.)
    • Asia Pacific (Vietnam, China, Malaysia, Japan, Philippines, Korea, Thailand, India, Indonesia and Australia)

    Get up to 50% off this report at: https://reportsglobe.com/ask-for-discount/?rid=176987

    Goals and Objectives of Valuation Fee Market Research

    • To understand the opportunities and progress of the Valuation Commission determines the highlights of the market, along with the key regions and countries involved in the growth of the market.
    • Study the different segments of the Assessment Board market and the dynamics of Assessment Board in the market.
    • Categorize the scorecard segments with increasing growth potential and assess the futuristic segment market.
    • To analyze the most important trends related to different segments which help decipher and convince the Assessment Board market.
    • Check region-specific growth and development in the Evaluation Board Market.
    • Understand the major stakeholders in the Valuation Consulting market and the value of the competitive image of the Valuation Consulting market leaders.
    • To study the key plans, initiatives, and strategies for the development of the Valuation Board Market.

    The study carefully examines the profiles of major market players and their key financial aspects. This comprehensive business analysis report is useful for all new and existing participants when designing their business strategies. This report covers the Evaluation Boards market production, revenue, market share and growth rate for each key company and covers broken down data (production, consumption, revenue and market share) by regions, type and apps. Valuation Commission Historical distribution data for 2016-2021 and forecast for 2022-2028.

    Ask your questions about personalization to: https://reportsglobe.com/need-customization/?rid=176987

    Some highlights from the table of contents:

    1 Presentation of the report

    2 Market Trends and Competitive Landscape

    3 Evaluation Board Market Segmentation by Types

    4 Evaluation Boards Market Segmentation by End Users

    5 Market Analysis by Major Regions

    6 Commodity of Evaluation Board Market Product by Major Countries

    7 North American Review Commission Landscape Analysis

    8 Analysis of the landscape of the European Evaluation Committee

    9 Asia Pacific Review Committee Landscape Analysis

    10 Latin America, Middle East and Africa Evaluation Committee Landscape Analysis

    11 Profile of Key Players

    How Reports Globe is different from other market research providers:

    The creation of Reports Globe has been underpinned by providing clients with a holistic view of market conditions and future possibilities/opportunities to derive maximum benefit from their business and assist in decision making. Our team of in-house analysts and consultants work tirelessly to understand your needs and provide the best possible solutions to meet your research needs.

    Our team at Reports Globe follows a rigorous data validation process, which allows us to publish publisher reports with minimal or no deviation. Reports Globe collects, separates and publishes over 500 reports each year covering products and services in many areas.

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    Website: Reportsglobe.com

  • ]]>
    Growth of the motorcycle instrument cluster market by 2029 https://topclusters.org/growth-of-the-motorcycle-instrument-cluster-market-by-2029/ Thu, 27 Jan 2022 00:06:07 +0000 https://topclusters.org/growth-of-the-motorcycle-instrument-cluster-market-by-2029/ New Jersey, United States,- This Motorcycle Instrument Cluster Market The report covers the business forecast for the years 2022-2029, along with the corporate strategy and industry size. It enters into the assessment of the competitive environment, which covers key demographics, classification and performance of customers. By providing an overview of markets and market-related statistics, this […]]]>

    New Jersey, United States,- This Motorcycle Instrument Cluster Market The report covers the business forecast for the years 2022-2029, along with the corporate strategy and industry size. It enters into the assessment of the competitive environment, which covers key demographics, classification and performance of customers. By providing an overview of markets and market-related statistics, this market research also helps participating companies maximize their presence in the industry. The market is further segmented on the basis of application, product category, end user, and location. All these crucial data will help the key players to outperform the competition and generate huge revenue for the business. It also offers beginners particular investment options to help them make lucrative trading decisions.

    Businesses can gain in-depth understanding of their clients with the help of notable data offered in the Motorcycle Instrument Cluster market report, and thus achieve their aim of selling items in bulk quantity while earning big profit . Setting a clear business goal from the start will help you avoid problems and get your business up and running quickly. The Motorcycle Instrument Cluster market report is generally drafted in easy-to-understand language to ensure the interaction is productive. The reviewer’s interest is captured by the market report’s use of engaging language. As a result, it leaves a lasting impact on the customers in the market.

    Get Sample Full PDF Copy of Report: (Including Full TOC, List of Tables & Figures, Chart) @ https://www.verifiedmarketreports.com/download-sample/?rid=61011

    Key Players Mentioned in the Motorcycle Instrument Cluster Market Research Report:

    Calsonic Kansei, Nippon Seiki, Visteon, J&P Cycles, JPM Group, Cluster Repairs, DIME CITY CYCLES, Texas Instruments, Pricol, Super Bright LEDs, MTA, Delphi Automotive

    Motorcycle Instrument Cluster Market Segmentation:

    By Product Type, the market is primarily split into:

    • Analog instrument cluster
    • Digital instrument cluster
    • Hybrid instrument cluster

    By application, this report covers the following segments:

    • Automobile industry
    • Mining industry
    • Construction industry
    • Traction industry
    • Electricity sector industry
    • Railway sector

    The motorcycle instrument cluster market is segmented on the basis of product type, application, and geography. All segments of the Motorcycle Instrument Cluster Market are carefully analyzed with respect to market share, CAGR, value and volume growth, and other significant factors. The report also provides accurate estimates on CAGR, revenue, production, sales, and other calculations for the Motorcycle Instrument Cluster market. Each regional market is studied in detail in the report to explain why some regions are growing at a high rate while others at a slow rate. We have also provided Porter’s Five Forces and PESTLE analysis for further study of the Motorcycle Instrument Cluster market.

    Get a discount on the purchase of this report @ https://www.verifiedmarketreports.com/ask-for-discount/?rid=61011

    Scope of the Motorcycle Instrument Cluster Market Report

    ATTRIBUTES DETAILS
    ESTIMATED YEAR 2022
    YEAR OF REFERENCE 2021
    FORECAST YEAR 2029
    HISTORICAL YEAR 2020
    UNITY Value (million USD/billion)
    SECTORS COVERED Types, applications, end users, and more.
    REPORT COVER Revenue Forecast, Business Ranking, Competitive Landscape, Growth Factors and Trends
    BY REGION North America, Europe, Asia-Pacific, Latin America, Middle East and Africa
    CUSTOMIZATION SCOPE Free report customization (equivalent to up to 4 analyst business days) with purchase. Added or changed country, region and segment scope.

    Geographic segment covered in the report:

    The Motorcycle Instrument Cluster report provides information on the market area, which is sub-divided into sub-regions and countries/regions. In addition to the market share in each country and sub-region, this chapter of this report also contains information on profit opportunities. This chapter of the report mentions the market share and growth rate of each region, country and sub-region over the estimated period.

    • North America (USA and Canada)
    • Europe (UK, Germany, France and rest of Europe)
    • Asia-Pacific (China, Japan, India and the rest of the Asia-Pacific region)
    • Latin America (Brazil, Mexico and rest of Latin America)
    • Middle East and Africa (GCC and Rest of Middle East and Africa)

    Answers to key questions in the report:

    1. Who are the top five players in the Motorcycle Instrument Cluster market?

    2. How will the Motorcycle Instrument Cluster Market change in the next 5 years?

    3. Which product and application will take the lion’s share of the motorcycle instrument cluster market?

    4. What are the drivers and restraints of Motorcycle Instrument Cluster Market?

    5. Which regional market will show the strongest growth?

    6. What will be the CAGR and size of the Motorcycle Instrument Cluster market throughout the forecast period?

    For more information or query or customization before buying, visit @ https://www.verifiedmarketreports.com/product/global-motorcycle-instrument-cluster-market-2018-by-manufacturers-regions-type-and-application-forecast-to-2023/

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    ]]>
    Coalition, including Eco Wave Power, chosen as a finalist in EDA’s Build Back Better Regional Challenge https://topclusters.org/coalition-including-eco-wave-power-chosen-as-a-finalist-in-edas-build-back-better-regional-challenge/ Tue, 18 Jan 2022 14:27:00 +0000 https://topclusters.org/coalition-including-eco-wave-power-chosen-as-a-finalist-in-edas-build-back-better-regional-challenge/ STOCKHOLM, January 18, 2022 /PRNewswire/ — Eco Wave Power Global AB (publ) (Nasdaq First North: ECOWVE, Nasdaq US: WAVE) (“Power of ecological waves“), a leader in generating clean electricity from oceans and waves, is proud to announce that it has been selected as a finalist as part of a coalition with other regional players in […]]]>

    STOCKHOLM, January 18, 2022 /PRNewswire/ — Eco Wave Power Global AB (publ) (Nasdaq First North: ECOWVE, Nasdaq US: WAVE) (“Power of ecological waves“), a leader in generating clean electricity from oceans and waves, is proud to announce that it has been selected as a finalist as part of a coalition with other regional players in the $1 billion Regional Build Back Better Challenge, led by the Los Angeles County Economic Development Corporation (LAEDC).

    At the time of the U.S. Economic Development Administration’s (“EDA”) announcement, Los Angeles Mayor Eric Garcetti said, “LAEDC and its community partners are doing such important work to ensure a strong and equitable economic recovery from the pandemic. This coalition embodies the spirit and innovation of our region, and I wish them success as they continue the second phase of this competition.”

    The EDA Challenge helps communities nationwide by accelerating economic recovery from the coronavirus pandemic and building local economies that will withstand future economic shocks. The Build Back Better Regional Challenge is the U.S. Department of Commerce’s biggest economic development initiative in decades.

    As a finalist, the coalition was rewarded $500,000 further develop plans for several coordinated projects to advance more equitable and sustainable growth in the region. The coalition will move to phase 2 and will compete until $100 million in US bailout funding to develop and scale blue and green growth innovations within the Goods Movement (GME) ecosystem by Southern California. This next step includes a proposal for the implementation of a first-of-its-kind pilot wave energy system at AltaSea at the Port of Los Angeles (“AltaSea”), a non-profit organization dedicated to accelerating scientific collaboration, fostering an emerging blue economy, and inspiring the next generation, all for a more sustainable, just world. and fair.

    Inna Braverman, founder and CEO of Power of ecological waves, said, “We are very proud to be part of the LAEDC-led coalition. We believe that we can contribute significantly to its mission to leverage the innate convergence of blue and green economies at the port of Los Angeles and beyond to create new jobs and businesses for the region, while improving the environment and increasing the resilience of America’s primary commercial gateway. We are excited to enter phase 2 of the program by implementing our innovative technology at AltaSea’s premises in the port of Los Angeles. This project will be the first time that clean electricity will be sent from ocean waves to Los Angeles electrical network.

    LAEDC brought together and facilitated a regional coalition of regional actors from government, business, non-profit organizations and academia. In addition to Power of ecological waves, stakeholders include AltaSea at Port of Los Angeles; the City of Los Angeles, headed by the mayor’s office Eric Garcetti and the city council; the Economic Development and Workforce Department (EWDD); LA Department of Water and Power (LADWP); Public works; LA Department of Transportation; the Port of Los Angeles; Toyota Motor North America; Shell; Los Angeles Cleantech Incubator (LACI); Urban Movement Laboratories (UML); Santa Monica College; the Los Angeles Regional Strong Workforce Consortium of 19 area community colleges; the Entrepreneur Education Center, Inc. (EECI) in South Los Angeles; the Long Beach Economic Partnership; and PledgeLA.

    The EDA received 529 applications from regions in all 50 states and five territories, and the 60 finalists represent regions that have formed extraordinary coalitions, demonstrated regional needs, and presented bold proposals to develop their target industry clusters. Ranging from rural communities and coastal cities to large metropolises, the finalists represent a diverse cross-section of the United States

    For the official press release on the AltaSea website, please see the following link: LAEDC’s Stephen Cheung on LA’s Build Back Better “Blue-Green” Regional Grants Challenge – AltaSea

    For the full list of members of the LAEDC-led coalition, please see the attached PDF, which is not part of this press release.

    About Eco Wave Power Global AB (publ)

    Power of ecological waves is a leading onshore wave energy technology company that has developed patented, smart and cost-effective technology to turn ocean and sea waves into green electricity. Eco Wave Power mission is to help fight climate change by enabling commercial electricity generation from the ocean and waves.

    Power of ecological waves is recognized as a “pioneering technology” by the Israeli Ministry of Energy and has been labeled an “Efficient Solution” by the Solar Impulse Foundation. The Eco Wave Power project in Gibraltar has received funding from the European Union Regional Development Fund and the European Commission’s Horizon 2020 framework programme. The company also received the “Global Climate Action Award” from the United Nations.

    Eco Wave Power the common stock (ECOWVE) is traded on the Nasdaq First North and its ADS (WAVE) is traded on the Nasdaq Capital Market.

    Vator Securities is the company’s Certified Advisor (+46 8 580 065 99, [email protected]).

    For more information please contact:

    Inna Braverman, CEO
    [email protected]
    +97235094017

    For any additional investor/media inquiries, please contact:

    Investor contacts:
    Matt Chesler, CFA
    FNK IR
    +1.646.809.2183
    [email protected]

    Media Contact:
    Allison & Partners
    [email protected]

    Forward-looking statements

    This press release contains forward-looking statements within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995 and other federal securities laws. Words such as “expects”, “anticipates”, “intends”, “plans”, “believes”, “seeks”, “estimates” and similar expressions or variations of these words are intended identify forward-looking statements. For example, Power of ecological waves uses forward-looking statements when discussing the Regional Build Back Better Challenge and its participation in Part II of the Regional Build Back Better Challenge, and its belief that it can contribute significantly to LAEDC’s mission to leverage the innate convergence of the blue and green economies at the port of Los Angeles and beyond to create new jobs and businesses for the region, while improving the environment and increasing the resilience of America’s primary commercial gateway. These forward-looking statements and their implications are based on the current expectations of the management of Power of ecological waves and are subject to a number of factors and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements. Unless otherwise provided by law, Power of ecological waves assumes no obligation to publicly release any revisions to these forward-looking statements to reflect events or circumstances after the date hereof or to reflect the occurrence of unforeseen events. More detailed information on the risks and uncertainties affecting Power of ecological waves is listed under the heading “Risk Factors” in Eco Wave Power Registration Statement on Form F-1 filed with the SEC, which is available at the SEC’s website, www.sec.gov.

    This information was brought to you by Cision http://news.cision.com

    https://news.cision.com/ewpg-holding-ab–publ-/r/coalition–incluant-eco-wave-power–chosen-as-a-finalist-in-eda-s-build- back-better-challe-regional,c3487495

    The following files are available for download:

    SOURCE EWPG Holding AB

    ]]>
    PCIe Slots Market Trends, Growth, Scope, Size, Global Analysis and Forecast by 2026 https://topclusters.org/pcie-slots-market-trends-growth-scope-size-global-analysis-and-forecast-by-2026/ Sat, 08 Jan 2022 14:22:17 +0000 https://topclusters.org/pcie-slots-market-trends-growth-scope-size-global-analysis-and-forecast-by-2026/ [ad_1] This recent study of the PCIe slots market contains an in-depth assessment of this industry vertical. According to the report, the market will register decent returns by the end of the forecast period, while registering a substantial growth rate throughout this period. PCIe Slots Market Size Growth Report | Industry Segment by Applications (External […]]]>


    [ad_1]

    This recent study of the PCIe slots market contains an in-depth assessment of this industry vertical. According to the report, the market will register decent returns by the end of the forecast period, while registering a substantial growth rate throughout this period.

    PCIe Slots Market Size Growth Report | Industry Segment by Applications (External GPUs, Storage Devices, Cluster Interconnect and Others), By Type (PCI-E X1, PCI-E X2, PCI-E X16 and others), Regional Outlook, Market Demand, Latest Trends, PCIe Slots Industry Share, Research Growth Forecast and Revenue by Manufacturers, Major Company Profiles, Growth Forecast – 2025.

    Request a copy of this report @ https://www.getnewsalert.com/request-sample/1779

    The report reveals significant insights into the PCIe Slots market and includes projections regarding the revenue, industry size, and sales volumes during the study period. Moreover, the PCIe Slots market report provides the detailed information regarding the industry segmentations along with the driving factors that will propel the profitability graph of the industry.

    This report studies the PCIe Slots market status and outlook for global and major regions, from the perspective of players, countries, product types and end industries, this report analyzes major players in the global industry PCIe slots, and is further divided by product type and applications / end industries. This report also includes the impact of COVID-19 on the PCIe Slot industry.

    An overview of the PCIe slots market in relation to the geographic landscape:

    • The PCIe Slots Market report examines the geographic landscape of this business sphere separating it into North America, Europe, Asia Pacific, Middle East & Africa, Latin America.
    • Important information regarding the sales accumulated by each region as well as their estimated market share is included in the report.
    • The report also shows the growth rate and returns for each geographic area over the projection period.

    PCIe Slots Competitive Landscape and Market Share Analysis:

    PCIe Slots competitive landscape provides details by vendors, including company overview, company total revenue (financials), market potential, global presence, sales and revenue generated by the PCIe Slots. PCIe slots, market share, price, production sites and facilities, SWOT analysis, product launch. For the period 2015-2020, this study provides the PCIe Slot sales, revenue and market share for each player covered in this report.

    Market segmentation : The PCIe slots market is segmented by type and by application. For the period 2015-2025, the growth among the segments provides accurate sales calculations and forecasts by type and by application in terms of volume and value. This analysis can help you grow your business by targeting qualified niche markets.

    Other important inclusions of the PCIe slots market are listed below:

    • An in-depth assessment of the competitive spectrum of the PCIe slots market has been presented in the report, with emphasis on the companies, namely Intel, IBM, LSI, OCZ, SanDisk, STEC, SuperTalent, Magma, Dell, Sonnet, Tp -link, Meinberg, Flyconn, TE and Molex.
    • A brief overview of the products offered by the major players and their scope are discussed in the report.
    • The study assesses the current position of companies in the market and documents the sales made by manufacturers.
    • The pricing models followed by these companies as well as the profit margins have been included in the report.
    • The study also lists the market shares held by companies.
    • The product line of PCIe slots market has been segregated into PCI-E X1, PCI-E X2, PCI-E X16 and others and elaborates on each product segment with respect to sales made and revenue accumulated over the course of the projection period.
    • The study also segments the scope of the products manufactured by major players and divides it into external GPUs, storage devices, cluster interconnect and others.
    • The market shares represented by each application segment according to their sales volume over the estimated duration are cited in the study.
    • The study also focuses on other business-oriented aspects of the market, such as the latest trends and the concentration rate.
    • The report provides information on the marketing and distribution channels of the major vendors.

    Research objectives:

    • To study and analyze the global PCIe Slots consumption (value and volume) by key regions / countries, type and application, historical data from 2016 to 2020, and forecast to 2026.
    • To understand the structure of PCIe Slots market by identifying its various subsegments.
    • Focuses on the world’s leading PCIe Connector manufacturers, to define, describe and analyze sales volume, value, market share, market competition landscape, SWOT analysis and development plans during the next few years.
    • To analyze the PCIe Slots industry with respect to individual growth trends, future prospects, and their contribution to the total market.
    • Share detailed information on the key factors influencing market growth (growth potential, opportunities, drivers, industry specific challenges and risks).
    • To project the consumption of PCIe Slot submarkets, with respect to key regions (along with their respective key countries).
    • Analyze competitive developments such as extensions, agreements, new product launches and acquisitions in the market.
    • To draw up a strategic profile of the main players and to analyze in depth their growth strategies.

    Questions answered by the report:

    • What will be the size of the global PCIe slots market in 2025?
    • What is the current CAGR of the global PCIe slots market?
    • Which product is expected to show the strongest growth in the market?
    • Which application is expected to gain share in the global PCIe slots market?
    • Which region is expected to create the most number of opportunities in the global PCIe slots market?
    • Will there be any changes in the competition in the market during the forecast period?
    • Who are the major players currently operating in the global PCIe slots market?
    • How will the market situation evolve in the years to come?
    • What are the common trading tactics adopted by players?
    • What is the growth outlook for the global PCIe slots market?

    Request customization on this report @ https://www.getnewsalert.com/request-for-customization/1779

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    ]]>
    Cluster Headache Syndrome Drugs Market 2021 by Types, Applications, and Major Key Players – GSK, Shanghai Soho-Yiming Pharmaceuticals, Center Laboratories Inc, Aurobindo, Par Pharmaceutical – Industrial IT https://topclusters.org/cluster-headache-syndrome-drugs-market-2021-by-types-applications-and-major-key-players-gsk-shanghai-soho-yiming-pharmaceuticals-center-laboratories-inc-aurobindo-par-pharmaceutical-industri/ Sat, 01 Jan 2022 17:40:01 +0000 https://topclusters.org/cluster-headache-syndrome-drugs-market-2021-by-types-applications-and-major-key-players-gsk-shanghai-soho-yiming-pharmaceuticals-center-laboratories-inc-aurobindo-par-pharmaceutical-industri/ [ad_1] The Cluster Headache Syndrome Drugs Market report is the foremost research for those looking for comprehensive information on the Cluster Headache Syndrome Drugs Markets. The report covers all the information on the global and regional markets including past and future trends for market demand, size, trade, supply, competitors and prices as well as information […]]]>


    [ad_1]

    The Cluster Headache Syndrome Drugs Market report is the foremost research for those looking for comprehensive information on the Cluster Headache Syndrome Drugs Markets. The report covers all the information on the global and regional markets including past and future trends for market demand, size, trade, supply, competitors and prices as well as information of global major vendors. . The report also provides a comprehensive overview of the cluster headache syndrome drugs markets; including top players or vendors, app, type, sharing, and the latest market trends.

    In-depth market analysis is combined with precise forecasts and projections in this Cluster Headache Syndrome Drugs Market report resulting in comprehensive research solutions that provide absolute clarity to the market report. industry for strategic decision making. Raw market data is collected and analyzed on a large scale. Data is also collected from a number of publications in our archives, as well as a number of well-known paid databases. The data in this Cluster Headache Syndrome Drugs market report has been gathered from raw material vendors, dealers, and customers to get a comprehensive understanding of the industry; therefore, this report is extremely helpful to the buyer.

    Cluster Headache Syndrome Drugs Market: Competition Landscape

    The Cluster Headache Syndrome Drugs Market report includes information on product launches, sustainability, and outlook for key vendors, including: (GSK, Shanghai Soho-Yiming Pharmaceuticals, Center Laboratories Inc, Aurobindo, Par Pharmaceutical, Fresenius Kabi, Sinopharm A-Think Pharmaceuticals, Sagent Pharmaceuticals, Eli Lilly and Company, Novartis AG, AstraZeneca, Teva Pharmaceutical Industries Ltd, Chengdu Tiantaishan Pharmaceutical, Sihuan Pharmaceutical Holdings Group, Yibin Pharmaceutical, Wockhardt, Pfizer, TrioxBio Inc, Sun Pharmaceutical)

    Click on the link for a free copy of the report @ https://crediblemarkets.com/sample-request/cluster-headache-syndrome-drug-market-544093?utm_source=Komal&utm_medium=SatPR

    Cluster Headache Syndrome Drugs Market: Segmentation

    The Cluster Headache Syndrome Drugs market is split by Type and by Application for the period 2021-2028, the growth among the segments provides accurate tips and sales forecast by type and by application in terms of volume and valuable. This analysis can help you grow your business by targeting qualified niche markets.

    By types:

    Triptans
    Octreotide
    Opioids
    Others

    By applications:

    Abortive
    Of transition
    Preventive

    Cluster Headache Syndrome Drugs Market: Regional Analysis

    All the regional segmentation has been studied on the basis of recent and future trends, and the market is forecast throughout the forecast period. Countries Covered in Regional Analysis of Global Cluster Headache Syndrome Drugs Market Report are United States, Canada and Mexico in North America, Germany, France, UK United, in Russia, in Italy, in Spain, in Turkey, in the Netherlands, in Switzerland, in Belgium and in the rest of Europe in Europe, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, China, Japan, India , South Korea, Rest of Asia-Pacific (APAC) Asia-Pacific (APAC), Saudi Arabia, United Arab Emirates, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) being part of the Middle East and Africa (MEA), and Argentina, Brazil and the rest of South America being part of South America.

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    Main points covered by the table of contents:

    To present: Besides a detailed overview of the global cluster headache syndrome drugs market, this segment provides an overview of the report to give insight into the nature and substance of the review study.

    Analysis of the strategies of the main players: Market players can use this analysis to gain a competitive advantage over their competitors in the Cluster Headache Syndrome Drugs market.

    Study on the main market trends: This part of the report offers a more meaningful assessment of recent and future examples of the market.

    Market Forecast: Buyers of the report will tackle accurate and approved valuations of all market sizes in terms of value and volume. The report further gives the usage, creation, offerings, and different conjectures for the Cluster Headache Syndrome Drugs market.

    Analysis of local growth: All critical regions and countries have been covered in the report. Neighborhood review will help uplift actors to exploit rejected common business areas, prepare express philosophies for target regions, and consider improving each regional market.

    Segmental analysis: The report gives precise and solid conjectures on a piece of the pie for important parts of the Cluster Headache Syndrome Drug market. Market members can use this review to pinpoint key interests in key development pockets of the market.

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    Key questions answered in the report:

    • What will be the pace of development of the Cluster Headache Syndrome Drug market?
    • What are the key factors driving the global cluster headache syndrome drugs market?
    • Who are the main manufacturers in the market?
    • What are the market openings, the market risks and the main lines of the market?
    • What are the sales, revenue, and price analysis of the major manufacturers of the Cluster Headache Syndrome Drug market?
    • Who are the distributors, traders and resellers of Cluster Headache Syndrome Drug market?
    • What are the opportunities and threats in the Cluster Headache Syndrome Drug market facing the vendors of the global Cluster Headache Syndrome Drug industries?
    • What is Offerings, Revenue, and Value Review by Types and Uses in the Market?
    • What is the Review of Transactions, Revenue and Value by Business Line?

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